Societal Costs and Benefits of Treatment with Trastuzumab in Patients with Early HER2neu-Overexpressing Breast Cancer in Singapore

Abstract Background Trastuzumab has revolutionized the way we treat early Her2Neu-positive breast cancer, as it significantly improves disease-free and Heel Cushion overall survival.Little is known about the societal costs and benefits of treatment with trastuzumab in the adjuvant setting in Southeast Asia.Methods Societal costs (benefits) were est

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Antihyperglycemic efficacy and safety of AKROPOL, a Persian medicine poly-herbal extract mixture, in the treatment of type 2 diabetic patients: a randomized, double-blind and placebo-controlled clinical trial

Background: In Iran, a variety of medicinal plants are used, either alone or in combination, for the treatment of diabetes mellitus (DM).However, scientific and clinical studies are needed to confirm the safety and efficacy of these medicinal plants.Objective: To evaluate the safety and efficacy of AKROPOL, a poly-herbal extract mixture used in Per

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The Role of Accumbal Hypoactivity in copyright Addiction.

copyright-induced hypoactivity of the nucleus accumbens (NAC) is hypothesized to contribute to copyright addiction.There are two important questions related to this hypothesis.First, copyright addiction is characterized by an increase in drug-directed behavior and a simultaneous weakening of other motivated behaviors.However, the NAC contributes to

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Worker Size Diversity Has No Effect on Overwintering Success under Natural Conditions in the Ant Temnothorax nylanderi

Winter is a difficult period for animals that live in temperate zones.It can inflict high mortality or induce weight loss with potential consequences on performance during the growing season.Social groups include individuals of various ages and sizes.This diversity may improve the ability of groups to buffer winter disturbances such as starvation o

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